I-Aminoguanidine Bicarbonate,ngefomula yamakhemikhali ch6n4co3 futhiI-CAS Inombolo 2582-30-1, iyingxenye yentshisekelo yezinhlelo zayo ezahlukahlukene kuma-Pharmaceuticals and Research. Inhloso yalesi sihloko ukwethula imikhiqizo ye-Aminoguanidine Bicarbonanine futhi icacise ukusetshenziswa kwayo nokubaluleka kwayo.
I-Aminoguanidine Bicarbonatekuyinto etholwa yi-guanidine, i-compaction eyenzeka ngokwemvelo ezitshalweni nasezinciphisweni. Kuyimpuphu emhlophe ye-crystalline enyakazisa kalula emanzini, okwenza kube lula ukuyisebenzisa ekwakhekeni okuhlukahlukene. Le nhlanganisela idonsele inzalo ngezakhiwo zayo ezingaba khona kwemithi kanye neqhaza layo ocwaningweni nasekuthuthukisweni.
Okunye kokusetshenziswa okuyinhloko kweI-Aminoguanidine Bicarbonateisensimini yezemithi. Kufundelwe amandla ayo njenge-ejenti yokulwa nama-glycation, okusho ukuthi kungasiza ukuvikela noma ukwehlisa ukwehlisa ukwakheka kwemikhiqizo ephambili ye-Glycation End (ubudala) emzimbeni. Iminyaka ihambisana nezifo ezihlobene nobudala obuhlobene nobudala, ezinjengesifo sikashukela, i-atherossteosis kanye nezifo ze-neurodegenerative. Ngokuvimbela ukwakheka kweminyaka yobudala, i-bicarbonanine bicarbonate ikhombisa isethembiso ekuthuthukiseni izidakamizwa ukuphatha lezi zifo.
Ngokwengeziwe, i-Aminoguanidine Bicarbonate CAS 2582-30-1 ifundelwe indima yayo ebiba khona ekwelapheni izinkinga ezinesifo sikashukela. Isifo sikashukela singaholela ezinkingeni ezahlukahlukene ezinjenge-nephropathy enesifo sikashukela, i-retinopathy, ne-neuroguanidine, futhi i-aninoguanidine bicarbonate ikhombisa amandla okunciphisa lezi zinkinga nge-antiglycation yayo nezakhiwo ze-antioxidant. Ukucwaninga kule ndawo kukhombisa ukuthi i-Compound iyakwazi ukunciphisa ukucindezela okuxakile futhi ivikele ukuxhumanisa amaprotheni, isici esiyisihluthulelo kuzinkinga zesifo sikashukela.
Ngaphezu kwezicelo zemithi,I-Aminoguanidine Bicarbonateisetshenziswa kumasethingi ocwaningo. Isetshenziswa ocwaningweni oluhlobene nokuxineka okuyi-oxidative, ukuvuvukala kanye nezifo ezihlobene nobudala. Ikhono le-Compound lokuguqula ukukhiqizwa kwe-nitric oxide kanye nezakhiwo zalo zokulwa nokuvuvukala kwenza kube yithuluzi elibalulekile lokuqonda izindlela eziphansi kwezifo ezahlukahlukene kanye nokwakha ukungenelela kokwelapha okungaba khona.
Kubalulekile ukuqaphela ukuthi yize ama-bicarbonaanidine bicarbonate akhombisa ukuthembisa izinkambu ezahlukahlukene, ukuqhubeka kokucwaninga kanye nokulingwa kwemitholampilo kuyadingeka ukuqonda ngokugcwele ukusebenza kwayo nokuphepha kwayo. Njenganoma iyiphi i-Compleccetical Compound, ukuhlolwa okuphelele nokuhlola kubalulekile ngaphambi kokusetshenziswa kwangaphambi kwezinjongo zokwelapha.
Ngokufigqiwe,I-Aminoguanidine Bicarbonate, nge-CAS Inombolo 2582-30-1, iyingxenye enamathuba emasimini ezenza ngemithi kanye nocwaningo. I-anti-glycation yayo, i-antioxidant kanye nezakhiwo zokulwa nokuvuvukala zenza kube ngumuntu ozongenela ucwaningo ukuba acwaninge ngezidakamizwa ezibhekene nezifo ezihlobene nobudala nezinkinga zesifo sikashukela. Njengoba ucwaningo luyaqhubeka kule ndawo, i-Aminoguanidine Bicarbonate inganikeza izindlela ezintsha zokuphathwa kwezimo zezempilo ezahlukahlukene, iveze indlela yokuthuthuka kokwelapha okungaba khona.
Isikhathi Seposi: Meyi-30-2024