I-aminoguanidine bicarbonate,ngefomula yamakhemikhali CH6N4CO3 kanyeInombolo ye-CAS 2582-30-1, iyinhlanganisela yentshisakalo yezinhlelo zayo ezihlukahlukene kwezemithi nocwaningo. Inhloso yalesi sihloko ukwethula imikhiqizo ye-aminoguanidine bicarbonate futhi icacise ukusetshenziswa kwayo kanye nokubaluleka kwayo.
I-Aminoguanidine bicarbonateiphuma ku-guanidine, inhlanganisela eyenzeka ngokwemvelo ezitshalweni nakuma-microorganisms. I-crystalline powder emhlophe encibilika kalula emanzini, okwenza kube lula ukusetshenziselwa ukwakheka okuhlukahlukene. Le nhlanganisela ihehe intshisekelo ngezakhiwo zayo ezingaba khona zemithi kanye neqhaza layo ocwaningweni nasekuthuthukisweni.
Enye yezinto ezisetshenziswa kakhului-aminoguanidine bicarbonateisendimeni yezemithi. Kuye kwacutshungulwa amandla ayo njenge-anti-glycation agent, okusho ukuthi ingasiza ekuvimbeleni noma ibambezele ukwakheka kwemikhiqizo esezingeni eliphezulu ye-glycation (AGE) emzimbeni. Iminyaka yobudala ihlotshaniswa nezifo ezihlukahlukene ezihlobene nobudala, njengesifo sikashukela, isifo sokuqina kwemithambo yegazi, kanye nezifo zemithambo-luvo. Ngokuvimbela ukwakheka kwama-AGE, i-aminoguanidine bicarbonate ikhombisa isithembiso ekwenzeni imithi yokwelapha lezi zifo.
Ukwengeza, i-aminoguanidine bicarbonate cas 2582-30-1 iye yacwaningwa ngendima yayo engaba khona ekwelapheni izinkinga zesifo sikashukela. Isifo sikashukela singaholela ezinkingeni ezihlukahlukene ezifana ne-nephropathy yesifo sikashukela, i-retinopathy, ne-neuropathy, kanti i-aminoguanidine bicarbonate ibonise amandla okudambisa lezi zinkinga ngokusebenzisa i-antiglycation yayo kanye ne-antioxidant. Ucwaningo kule ndawo lubonisa ukuthi i-compound iyakwazi ukunciphisa ukucindezeleka kwe-oxidative futhi ivimbele amaprotheni cross-linking, isici esiyinhloko ezinkingeni zesifo sikashukela.
Ngaphezu kwezicelo zemithi,i-aminoguanidine bicarbonateisetshenziswa ezindaweni zocwaningo. Isetshenziselwa ucwaningo oluhlobene nokucindezeleka okwenziwe nge-oxidative, ukuvuvukala kanye nezifo ezihlobene neminyaka. Ikhono le-compound lokulinganisa ukukhiqizwa kwe-nitric oxide kanye nezindawo zayo zokulwa nokuvuvukala kuyenza ibe ithuluzi elibalulekile lokuqonda izindlela eziyisisekelo zezifo ezihlukahlukene kanye nokuthuthukisa ukungenelela okunamandla okwelapha.
Kubalulekile ukuqaphela ukuthi nakuba i-aminoguanidine bicarbonate ibonisa isithembiso emikhakheni eyahlukene, ucwaningo olwengeziwe kanye nokuhlolwa komtholampilo kuyadingeka ukuze kuqondwe ngokugcwele ukusebenza kahle nokuphepha kwayo. Njenganoma iyiphi inhlanganisela yemithi, ukuhlolwa okuphelele nokuhlolwa kubalulekile ngaphambi kokusetshenziswa kabanzi ngezinjongo zokwelapha.
Ngokufigqiwe,i-aminoguanidine bicarbonate, enenombolo ye-CAS 2582-30-1, iyinhlanganisela enamandla emikhakheni yezemithi nocwaningo. I-anti-glycation yayo, i-antioxidant kanye ne-anti-inflammatory properties iyenza ingenele ucwaningo lokuthuthukisa izidakamizwa ezilwa nezifo ezihlobene nobudala kanye nezinkinga zesifo sikashukela. Njengoba ucwaningo luqhubeka kule ndawo, i-aminoguanidine bicarbonate ingase inikeze izindlela ezintsha zokuphatha izimo zezempilo ezihlukahlukene, ivule indlela yentuthuko engase ibe khona yokwelapha.
Isikhathi sokuthumela: May-30-2024