Ingabe i-5-hydroxymeteteylfurural iyingozi?

I-5-hydroxymethylurfiral (5-HMF), futhi yi-CAS 67-47-0, iyinhlangano yemvelo yemvelo ethathwe ushukela. Kungumkhawulo oyisihluthulelo ekukhiqizweni kwamakhemikhali ahlukahlukene, asetshenziswa njenge-ejenti yokunambitha embonini yezidlo, futhi asetshenziswa ekuhlanganiseni kwezidakamizwa ezahlukahlukene embonini yezemithi. Kodwa-ke, kukhona ukukhathazeka ngemiphumela engaba yingozi ye-5-hydroxymeteylfurfiral ngempilo yabantu.

I-5-hydroxymethylurfiralKuvame ukutholakala ekudleni okuhlukahlukene okulungiswe ukushisa, ikakhulukazi lawo aqukethe ushukela noma isiraphu ye-corn ephakeme. Kwakheka ngesikhathi sokuphendula kwe-maillard, ukusabela kwamakhemikhali phakathi kwama-amino acid futhi kunciphisa ushukela owenzeka lapho ukudla kufudumele noma kuphekwe. Ngenxa yalokho,I-5-HMFKutholakala ekudleni okuhlukahlukene okucutshunguliwe, kufaka phakathi izimpahla ezibhakiwe, izithelo ezikheniwe nemifino, nekhofi.

Imiphumela engaba yingozi yeI-5-hydroxymethylurfiralkube yisihloko socwaningo lwesayensi kanye nempikiswano. Ezinye izifundo zibonisa ukuthi amazinga aphezulu angu-5-HMF ekudleni angahlotshaniswa nemiphumela emibi yezempilo, kufaka phakathi i-genotoxicity ne-carcinogenicity. I-Genotoxicity ibhekisela emandleni amakhemikhali ukulimaza imininingwane yofuzo ngaphakathi kwamaseli, okuholela ekuguqukeni kwezakhi zofuzo noma umdlavuza. I-carcinogenicicity, ngakolunye uhlangothi, isho amandla wento yokwenza umdlavuza.

Kodwa-ke, kufanelekile ukuqaphela ukuthi amazingaI-5-hydroxymethylurfiralOkuningi ukudla ngokuvamile kubhekwa njengokuphephile ukusetshenziswa kwabantu. Ama-ejensi okulawula afana nokudla kwe-US Food and Drug Administration (FDA) kanye ne-European Food Safety Authority (EFSA) athuthukise imihlahlandlela yamazinga amukelekile e-5-HMF ekudleni. Le mihlahlandlela isuselwa ocwaningweni olunzulu lwesayensi futhi lwenzelwe ukuqinisekisa ukuphepha kwabathengi.

Ngaphezu kokubakhona kwayo ekudleni, kusetshenziswa ama-5-hydroxymeteylfurfiral ezisekelweni ezahlukahlukene zezimboni. Kungumkhawulo oyisihluthulelo ekukhiqizweni kwamakhemikhali we-furan, asetshenziselwa ukwenza ama-resins, amapulasitiki kanye nemithi. I-5-HMF nayo iyafundwa njengengxenye yesikhulumi esekwe nge-bio esekelayo yokukhiqizwa kwama-fuel namakhemikhali avuselelekayo.

Noma kunezinto ezikhathazayo ngemiphumela elimazayo yeI-5-hydroxymethylurfiral, kubalulekile ukuqaphela ukuthi le nhlanganisela futhi inezicelo ezibalulekile zezimboni futhi ingukukhiqizwa okungokwemvelo kokupheka nokushisa ukudla. Njengamakhemikhali amaningi, ukhiye wokuqinisekisa ukuphepha ukubheka ngokucophelela futhi ulawule amazinga awo okusetshenziswa nokuvezwa.

Ngokufingqa, kuyilapho kukhona okukhathazayo ngemiphumela engaba yingozi yeI-5-hydroxymethylurfiral, ikakhulukazi ezihlobene nokuba khona kwayo ekudleni, ubufakazi besayensi yamanje buqinisekisa ukuthi likhona ekudleni okuningi ngamazinga ngokuvamile kubhekwa njengokuphephile kokusetshenziswa kwabantu. Ama-ejensi okulawula athuthukise imihlahlandlela yokuqinisekisa ukuphepha kwabathengi, futhi izifundo ziyaqhubeka nokuqonda imiphumela yezempilo engaba khona. Njenganoma yimaphi amakhemikhali, kubalulekile ukuqhubeka nokubheka ukusetshenziswa kwawo kanye namazinga okuvezwa ukuze uqinisekise ukuphepha kwabathengi nabasebenzi embonini.