I-5-Hydroxymethylfurfural (5-HMF), futhi i-CAS 67-47-0, iyinhlanganisela yemvelo yemvelo etholakala kushukela. Kuyisihluthulelo esimaphakathi ekukhiqizeni amakhemikhali ahlukahlukene, asetshenziswa njenge-ejenti yokunambitha embonini yokudla, futhi asetshenziswa ekuhlanganiseni kwezidakamizwa ezinhlobonhlobo embonini yezemithi. Nokho, kukhona ukukhathazeka mayelana nemiphumela eyingozi engaba khona ye-5-hydroxymethylfurfural empilweni yabantu.
5-Hydroxymethylfurfuralivame ukutholakala ekudleni okuhlukahlukene okukhiqizwa ngokushisa, ikakhulukazi okuqukethe ushukela noma isiraphu yommbila ene-fructose ephezulu. Yakha ngesikhathi sokusabela kwe-Maillard, ukusabela kwamakhemikhali phakathi kwama-amino acid nokunciphisa ushukela okwenzeka lapho ukudla kushisa noma kuphekiwe. Ngenxa yalokho,5-HMFitholakala ezinhlobonhlobo zokudla okugayiwe, okuhlanganisa izinto ezibhakwayo, izithelo nemifino ekheniwe, kanye nekhofi.
Imiphumela engaba yingozi ye5-hydroxymethylfurfuralbekuyindaba yocwaningo lwesayensi nenkulumo-mpikiswano. Ezinye izifundo ziphakamisa ukuthi amazinga aphezulu we-5-HMF ekudleni angase ahlotshaniswe nemiphumela emibi yezempilo, kuhlanganise ne-genotoxicity kanye ne-carcinogenicity. I-Genotoxicity ibhekisela emandleni amakhemikhali okulimaza ulwazi lofuzo ngaphakathi kwamaseli, okungase kuholele ekuguqukeni kwezakhi zofuzo noma umdlavuza. I-Carcinogenicity, ngakolunye uhlangothi, ibhekisela emandleni ento ukubanga umdlavuza.
Nokho, kuyaphawuleka ukuthi amazinga5-hydroxymethylfurfuralekudleni okuningi ngokuvamile kubhekwa njengokuphephile ukudliwa abantu. Ama-ejensi alawulayo afana ne-US Food and Drug Administration (FDA) kanye ne-European Food Safety Authority (EFSA) benze imihlahlandlela yamazinga amukelekayo we-5-HMF ekudleni. Le mihlahlandlela isekelwe ocwaningweni olunzulu lwesayensi futhi yakhelwe ukuqinisekisa ukuphepha kwabathengi.
Ngaphezu kokuba khona kwayo ekudleni, i-5-hydroxymethylfurfural isetshenziswa ezinhlelweni ezahlukahlukene zezimboni. Kuyisihluthulelo esimaphakathi ekukhiqizeni amakhemikhali e-furan, asetshenziselwa ukwenza ama-resin, amapulasitiki kanye nemithi. I-5-HMF nayo iyacwaningwa njengekhemikhali yesikhulumi se-bio-based engaba khona ukuze kukhiqizwe amafutha avuselelekayo namakhemikhali.
Nakuba kunokukhathazeka ngemiphumela eyingozi ye5-hydroxymethylfurfural, kubalulekile ukuqaphela ukuthi le nhlanganisela nayo inezinhlelo zokusebenza ezibalulekile zezimboni futhi i-byproduct yemvelo yokupheka nokushisa ukudla. Njengamakhemikhali amaningi, isihluthulelo sokuqinisekisa ukuphepha ukuqapha ngokucophelela nokulawula ukusetshenziswa kwawo kanye namazinga okuchayeka.
Kafushane, nakuba kukhona ukukhathazeka mayelana nemiphumela eyingozi engase ibe khona5-hydroxymethylfurfural, ikakhulukazi ehlobene nokuba khona kwayo ekudleni, ubufakazi bamanje besayensi buphakamisa ukuthi ikhona ekudleni okuningi emazingeni ngokuvamile abhekwa njengokuphephile ukudliwa abantu. Ama-ejensi alawulayo asungule imihlahlandlela yokuqinisekisa ukuphepha kwabathengi, futhi ucwaningo luyaqhubeka ukuze kuqondwe kabanzi imiphumela yezempilo engaba khona yenhlanganisela. Njenganoma iyiphi ikhemikhali, kubalulekile ukuqhubeka nokuqapha ukusetshenziswa kwayo kanye namazinga okuchayeka ukuze kuqinisekiswe ukuphepha kwabathengi nabasebenzi embonini.
Isikhathi sokuthumela: May-29-2024