Tranexamic acid 1197-18-8

1. Aṣoju Antifibrinolytic; ohun amorindun lysine abuda ojula ti plasminogen. Hemostatic.

2. Ti a lo bi afọwọṣe lysine lati ṣe apejuwe awọn aaye abuda ni plasminogen

3. Fibrinolysis, fifọ fibrin nipasẹ plasmin, jẹ igbesẹ deede ni itusilẹ awọn didi fibrin lẹhin atunṣe ọgbẹ. Tranexamic acid jẹ oludena fibrinolysis ti o ṣe idiwọ ibaraenisepo ti plasmin pẹlu fibrin (IC50 = 3.1 μM). O jẹ mimetic lysine ti o sopọ mọ aaye lysine ni plasmin. Awọn aṣoju Antifibrinolytic ni iye nigbati iṣẹ-ṣiṣe fibrinolytic ba ga pupọ tabi nigbati coagulation ba bajẹ.