Aminoguanidine bicarbonate,kunye nefomula yeekhemikhali CH6N4CO3 kunyeInombolo ye-CAS 2582-30-1, yinkomponi yomdla kwizicelo zayo ezahlukeneyo kumayeza kunye nophando. Injongo yeli nqaku kukwazisa iimveliso ze-aminoguanidine bicarbonate kwaye zicacise ukusetyenziswa kwazo kunye nokubaluleka.
Aminoguanidine bicarbonateiphuma kwi-guanidine, ikhompawundi eyenzeka ngokwemvelo kwizityalo nakwi-microorganisms. Ingumgubo omhlophe we-crystalline oxutywa lula emanzini, okwenza kube lula ukuyisebenzisa kwiintlobo ezahlukeneyo zokuqulunqa. Le khompawundi itsale umdla kwiipropati zayo ezinokubakho ze-pharmacological kunye nendima yayo kuphando nophuhliso.
Enye yosetyenziso oluphambili lweaminoguanidine bicarbonateikwicandelo lamachiza. Kuye kwafundwa ngokukwazi kwayo njenge-anti-glycation agent, oku kuthetha ukuba kunokunceda ukukhusela okanye ukucotha ukubunjwa kweemveliso zokugqibela ze-glycation (AGE) emzimbeni. Ii-AGEs zinxulunyaniswa nezifo ezahlukahlukeneyo ezinxulumene nobudala, njengesifo seswekile, i<em>atherosclerosis , nezifo zemithambo-luvo. Ngokuthintela ukubunjwa kwee-AGEs, i-aminoguanidine bicarbonate ibonisa isithembiso ekuphuhliseni amachiza okunyanga ezi zifo.
Ukongezelela, i-aminoguanidine bicarbonate cas 2582-30-1 ifundwe ngendima enokubakho kunyango lweengxaki zeswekile. Isifo seswekile sinokukhokelela kwiingxaki ezahlukeneyo ezifana ne-nephropathy yesifo sikashukela, i-retinopathy, kunye ne-neuropathy, kunye ne-aminoguanidine bicarbonate ibonise amandla okunciphisa ezi ngxaki ngokusebenzisa i-antiglycation kunye ne-antioxidant properties. Uphando kule ndawo lubonisa ukuba i-compound iyakwazi ukunciphisa uxinzelelo lwe-oxidative kunye nokukhusela i-protein cross-linking, eyona nto iphambili kwiingxaki zesifo sikashukela.
Ukongeza kwizicelo zamayeza,aminoguanidine bicarbonateisetyenziswa kwiindawo zophando. Isetyenziselwa uphando olunxulumene noxinzelelo lwe-oxidative, ukuvuvukala kunye nezifo ezinxulumene neminyaka. Ikhono le-compound ukulungelelanisa ukuveliswa kwe-nitric oxide kunye neempawu zayo ezichasayo zenza ukuba kube sisixhobo esixabisekileyo sokuqonda iindlela eziphantsi kwezifo ezahlukahlukeneyo kunye nokuphuhlisa iindlela zokungenelela zonyango.
Kubalulekile ukuqaphela ukuba nangona i-aminoguanidine bicarbonate ibonisa isithembiso kwiinkalo ezahlukeneyo, uphando olongezelelweyo kunye novavanyo lweklinikhi luyafuneka ukuze kuqondwe ngokupheleleyo ukusebenza kwayo kunye nokhuseleko. Njengayo nayiphi na ikhompawundi yoxubo mayeza, uvavanyo olucokisekileyo kunye novavanyo lubalulekile ngaphambi kokusetyenziswa ngokubanzi kwiinjongo zonyango.
Isishwankathelo,i-aminoguanidine bicarbonate, enenombolo ye-CAS 2582-30-1, yikhompawundi enesakhono kwiinkalo zokwenza amayeza kunye nophando. I-anti-glycation yayo, i-antioxidant kunye ne-anti-inflammatory properties yenza ukuba ibe ngumviwa wophando ekuphuhliseni iziyobisi ezichasene nezifo ezinxulumene neminyaka kunye neengxaki zesifo sikashukela. Njengoko uphando luqhubeka kule ndawo, i-aminoguanidine bicarbonate inokubonelela ngeendlela ezintsha zokulawula iimeko ezahlukeneyo zempilo, ivule indlela yokuqhubela phambili kwezonyango.
Ixesha lokuposa: May-30-2024