IClecoxib CAS 169590-42-5

IClecoxib cas 169590-425-5 iboniswe umfanekiso
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Inkcazo emfutshane:

IClecoxib sisiyobisi esingavunyiweyo i-Anti-i-ivolmaid Ihlala ilungiselelwe ulawulo ngomlomo kwiicapsules ezinokuba yi-getitinous kwaye iza kwimibala eyahlukeneyo, kuxhomekeka kuMvelisi.

IClecoxib inyibilikiswe kakuhle emanzini kodwa inyibilikiswe kakhulu kwiinyibiliki ezifana ne-ethanol kunye ne-methanol. Ukunyibilisela kwawo emanzini bumalunga ne-0.5 mg / ml nge-25 ° C. Olu lonwabo olunqongopheleyo kwizisombululo ze-ACOOCT luqwalaselo olubalulekileyo lokuqulunqwa nokunyanzelwa kwayo.

 


Iinkcukacha zemveliso

Iimpawu zeMveliso

Ingcaciso yeMveliso

Igama lemveliso: iCelecoxib
I-CAS: 169590-42-5
Mf: c17h14F3N3N3O
MW: 381.37
I-Einecs: 685-962-5
Inqaku lokunyibilika: I-157-159 ° C
Inqaku lokubila: 529.0 ± 60 ° C (iqikelelwe)
Ukuxinana: 1.43 ± 0.1 g / cm3 (kuxelwe kwangaphambili)
Indawo yokugcina: 2-8 ° C
I-Solkobay DMO:> 20mg / ml
I-PKA: 9.68 ± 0.10 (iqikelele)
IFOMU: IPOLDER
Umbala: White ukuya kwi-Off-White
I-Solity yaManzi: I-7MG / L (25 ºC)
I-Merck: 14,1956

Ukucaciswa

Igama lemveliso I-Celecoxib
Imbonakalo Mhlophe ukuya kwi-blostalline ye-rystalline powder
Ubunyulu I-99% imiz
MW 381.37
Indawo yokunyibilika I-157-159 ° C

Isicelo

1. Ukunyangwa kwesifo samathambo, kuchasene nefuthe lemiphumo kunye ne-analgesic, kwaye unciphise iimpawu kunye neempawu ze-osteoarthritis kunye ne-rumatoid Arthritis.
2. Iziyobisi zokunyanga isifo samathambo.
I-3. Ngonyango lwe-Ostomatic ye-Osteoarthritis kunye neRheumatoid Arthritis.

 

I-1. Osteoarthritis:Ikhulula intlungu kunye nokuvuvukala okunxulumene nesi sifo sidibeneyo.
I-2. I-Rheumatoid Arthritis:Lawula iimpawu zesifo se-autoimmune.
3. Intlungu enkulu:Isetyenziselwa isiqabu sexesha elifutshane, ezinjengentlungu emva kotyando okanye ukwenzakala.
4. Dysmenorhea:Hlaziya iintlungu ezinxulunyaniswa nokuya esikhathini.
I-5. I-Adenomatous Polypossis (PFE):Kwiimeko ezithile, iClecoxib inokusetyenziselwa ukunciphisa inani leepolip kwizigulana ezinezi sifo semfuzo.

 

Intlawulo

1, t / t

2, l / c

3, Visa

4, Ikhadi letyala

I-5, PayPal

I-6, iAlibhaba isiqinisekiso sokusebenza

I-7, i-Western Union

I-8, iMoneyGram

I-9, ngamanye amaxesha siyayamkela i-bitcoin.

intlawulo

Ukugcinwa

Le mveliso kufuneka igcinwe kwindawo epholileyo nemnyama.

Tywina isikhongozeli kwaye uyigcine kwisikhongozeli esiyintloko esiyisiseko, kwindawo eyomileyo.

 

I-1. Iqondo lokushisa: i-Delogy kubushushu begumbi, ngokubanzi phakathi kwe-20 ° C ukuya kwi-25 ° C (68 ° F ukuya kwi-77 ° F). Kulumkele ukuveza ubushushu obugqithisileyo.

2. Ukufuma: ivenkile kwindawo eyomileyo, kude nokufuma. Kulumkele ukugcina kwigumbi lokuhlambela okanye ezinye iindawo ezinomswakatha.

3. Ukuvezwa kokukhanya: Gcina iyeza lesikhongozeli loqobo, kuvaliwe kwaye kungekho kude nokukhanya.

4. Bantwana kunye nezilwanyana zasekhaya: Nceda ugcine le mveliso ingafikeleleki kubantwana kunye nezilwanyana zasekhaya ukuthintela ukuqhutywa ngengozi.

5. Umhla wokuphelelwa: Soloko ujonga umhla wokuphelelwa kwipakethe kwaye uchithe ngokufanelekileyo naluphi na unyango olupheleyo.

 

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Inkcazo yamanyathelo oncedo afunekayo

Ingcebiso ngokubanzi
Nxibelelana nod. Veza le phepha ledatha lokhuseleko luye kugqirha kwisiza.
Inhale
Ukuba ukhanjiswe, hambisa isigulana kumoya omtsha. Ukuba ukuphefumla kuyayeka, phumla ukuphefumla okuphezulu. Nxibelelana nod.
Unxibelelwano lwesikhumba
Hlamba ngesepha kunye namanzi amaninzi. Nxibelelana nod.
uqhagamshelo lamehlo
Gusha amehlo ngamanzi njengenyathelo lokuthintela.
Ingetion
Ungaze unike nantoni na ngomlomo nomntu ongazi nto. Hlamba umlomo wakho ngamanzi. Nxibelelana nod.

Ngaba iClecoxib ingozi?

I-1. Iziphumo ebezingalindelekanga: Iziphumo ebezingalindelekanga eziqhelekileyo zibandakanya iingxaki ze-gestrointenal (njengeentlungu zesisu, isisu kunye ne-hausea), intloko ebuhlungu, isiyezi kunye ne-rash. Iziphumo ezibi eziphakamileyo zibandakanya i-Cardiovasculars (ezinjengokuhlaselwa kwentliziyo okanye ukubetha), iingxaki ze-gestrointeltenal kunye neengxaki zezintso.

2. Ukuphendula ngokungalunganga: Abanye abantu banokuba nentsingiselo yokuphendula kwiCelecoxib, enokubonisa njengokuphefumla, okanye ukudumba kobuso, imilebe, okanye umqala.

3. Abantu abaphikisanayo: Abantu abanezithuba ezithile zonyango kufuneka bakuphephe ukusebenzisa iCelecoxib, i-Aspirin Anti-i-Antiridal, kunye nezona ngxaki zibuhlungu, zisibindi.

4. Unxibelelwano lweziyobisi: iCizecoxi inokuthi inxibelelane namanye amayeza, anokunyusa umngcipheko weziphumo ebezingalindelekanga okanye unciphise ukusebenza kwamayeza.

I-5. Ukukhulelwa kunye nokuncancisa ibele: iCicoxib ngokubanzi ayicetyiswa ukuba isetyenziswe ngexesha lokukhulelwa, ngakumbi kwi-trimester yesithathu, kwaye icetyiswa ukuba isetyenziswe ngononophelo ngoomama abancancisayo.

 

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