1. Hormone e hlahisoang e le lipakeng tsa photoperiodicity ho liphoofolo tse anyesang. E thibela cerebellar nitric oxide synthetase
2. Melatonine e ka sebelisoa ho kenyelletsa boroko, e fetola morethetho oa circadian, antioxidant, free radical scavenger.
3. Immunostimulant;Melatonin receptor ligand
4. Melatonin e na le liphello tse rarahaneng litseleng tsa apoptotic, e thibela apoptosis liseleng tsa 'mele le li-neuron empa e ntlafatsa lefu la apoptotic ea lisele tsa kankere. E thibela ho ata/metastasis ea lisele tsa mofetše oa matsoele ka ho thibela ketso ea estrogen receptor.