Aminoguanidine bicarbonate,oo leh qaacidada kiimikada CH6N4CO3 iyoLambarka CAS 2582-30-1, waa isku-darka xiisaha codsiyada kala duwan ee daawooyinka iyo cilmi-baarista. Ujeedada maqaalkani waa in la soo bandhigo alaabada aminoguanidine bicarbonate oo caddeeyo isticmaalkooda iyo muhiimadooda.
Aminoguanidine bicarbonatewaa nooc ka mid ah guanidine, oo ah ka samaysan dabiici ah oo ku jira dhirta iyo noolaha. Waa budo crystalline cad oo si fudud ugu milmay biyaha, taas oo sahlaysa in loo isticmaalo qaabab kala duwan. Xaruntan ayaa soo jiidatay xiisaha ay u leedahay sifooyinka dawooyinka ee suurtogalka ah iyo doorka ay ku leedahay cilmi-baarista iyo horumarinta.
Mid ka mid ah isticmaalka ugu muhiimsan eeaminoguanidine bicarbonatewaxay ku jirtaa goobta dawooyinka. Waxaa lagu bartay awooddeeda sida wakiilka ka-hortagga glycation, taasoo la micno ah inay kaa caawin karto ka hortagga ama hoos u dhigida sameynta alaabada dhamaadka glycation sare (AGE) ee jirka. AGE-yada waxay la xiriiraan cudurro kala duwan oo la xiriira da'da, sida sonkorowga, atherosclerosis, iyo cudurrada neurodegenerative. Iyadoo la xakameynayo samaynta AGE-yada, aminoguanidine bicarbonate waxay muujinaysaa ballan-qaadka horumarinta daawooyinka lagu daweeyo cudurradan.
Intaa waxaa dheer, aminoguanidine bicarbonate cas 2582-30-1 ayaa lagu bartay doorkeeda suurtagalka ah ee daaweynta dhibaatooyinka sonkorowga. Sonkorowga ayaa u horseedi kara dhibaatooyin kala duwan sida nephropathy sonkorowga, retinopathy, iyo neuropathy, iyo aminoguanidine bicarbonate waxay muujisay karti ay ku yareyn karto dhibaatooyinkan iyada oo loo marayo antiglycation iyo sifooyinka antioxidant. Cilmi-baadhista aaggan ayaa muujinaysa in xaruntu ay awood u leedahay inay hoos u dhigto cadaadiska oksaydhka iyo ka hortagga isku-xidhka borotiinka, oo ah arrin muhiim ah oo ku saabsan dhibaatooyinka sonkorowga.
Marka laga reebo codsiyada dawooyinka,aminoguanidine bicarbonatewaxaa loo isticmaalaa goobaha cilmi-baarista. Waxaa loo adeegsadaa cilmi-baarista la xiriirta cadaadiska oksaydhka, bararka iyo cudurrada da'da la xiriira. Awoodda isku-dhafka ah ee lagu beddelo wax-soo-saarka nitric oxide iyo sifooyinkeeda ka-hortagga bararka ayaa ka dhigaya qalab qiimo leh oo lagu fahmo hababka ka hooseeya cudurrada kala duwan iyo horumarinta waxqabadyo daweyn oo suurtagal ah.
Waxaa muhiim ah in la ogaado in inkasta oo aminoguanidine bicarbonate ay muujinayso ballanqaad dhinacyo kala duwan, cilmi-baaris dheeraad ah iyo tijaabooyin caafimaad ayaa loo baahan yahay si loo fahmo waxtarkeeda iyo badbaadada. Sida xarun kasta oo dawooyin ah, qiimayn buuxda iyo tijaabin waa muhiim ka hor inta aan si baahsan loo isticmaalin ujeedooyinka daawaynta.
Isku soo wada duubooaminoguanidine bicarbonate, oo leh lambarka CAS 2582-30-1, waa xarun awood u leh dhinacyada dawooyinka iyo cilmi-baarista. Its anti-glycation, antioxidant iyo sifooyinka anti-bararka ayaa ka dhigaya musharax u ah cilmi-baarista horumarinta daawooyinka ka hortagga cudurrada da'da la xiriira iyo dhibaatooyinka sonkorowga. Sida cilmi-baaristu ay uga sii socoto aaggan, aminoguanidine bicarbonate waxay bixin kartaa wadooyin cusub oo lagu maareeyo xaalado caafimaad oo kala duwan, taasoo u gogol xaareysa horumarka daweynta ee suurtagalka ah.
Waqtiga boostada: Meey-30-2024