Aminoguanidine bicarbonate,nemakemikari formula CH6N4CO3 uyeNhamba yeCAS 2582-30-1, musanganiswa wekufarira kwekushandisa kwayo kwakasiyana mumishonga nekutsvaga. Chinangwa chechinyorwa chino kuunza zvigadzirwa zveaminoguanidine bicarbonate uye kujekesa mashandisiro azvo uye kukosha kwazvo.
Aminoguanidine bicarbonateinotorwa kubva ku guanidine, musanganiswa unongoitika mumiti uye tupukanana. Iyo chena crystalline powder inonyungudika nyore nyore mumvura, zvichiita kuti zvive nyore kushandisa mumhando dzakasiyana-siyana. Komisheni iyi yakwezva kufarira kune inogona kuita pharmacological zvimiro uye basa rayo mukutsvaga nekusimudzira.
Imwe yemashandisirwo makuru eaminoguanidine bicarbonateiri mumunda wemishonga. Yakave yakadzidzwa nokuda kwekugona kwayo se-anti-glycation agent, zvinoreva kuti inogona kubatsira kudzivirira kana kuderedza kuumbwa kwepamusoro glycation end products (AGE) mumuviri. AGE anobatanidzwa nezvirwere zvakasiyana-siyana zvine chokuita nezera, zvakadai seshuga, atherosclerosis, uye neurodegenerative zvirwere. Nekudzivisa kuumbwa kwemaAGE, aminoguanidine bicarbonate inoratidza chivimbiso mukugadzira mishonga yekurapa zvirwere izvi.
Pamusoro pezvo, aminoguanidine bicarbonate cas 2582-30-1 yakadzidzwa nezve basa rayo rinogona kuita mukurapa kwechirwere cheshuga. Chirwere cheshuga chinogona kutungamirira kumatambudziko akasiyana-siyana akadai sechirwere cheshuga nephropathy, retinopathy, neuropathy, uye aminoguanidine bicarbonate yakaratidza kukwanisa kuderedza matambudziko aya kuburikidza nehutachiona hwehutachiona uye antioxidant. Tsvagiridzo munharaunda ino inoratidza kuti komputa inokwanisa kuderedza oxidative kusagadzikana uye kudzivirira mapuroteni cross-linking, chinhu chakakosha mumatambudziko eshuga.
Pamusoro pekushandiswa kwemishonga,aminoguanidine bicarbonateinoshandiswa mumaseti ekutsvagisa. Inoshandiswa mukutsvagisa ine chekuita neoxidative kusagadzikana, kuzvimba uye zvirwere zvine chekuita nezera. Iko kugona kwekomboni kugadziridza nitric oxide kugadzirwa uye anti-kuzvimba zvimiro inoita kuti ive chishandiso chakakosha chekunzwisisa magadzirirwo ari pasi pezvirwere zvakasiyana siyana uye kugadzira zvingangoita zvekurapa.
Zvakakosha kuziva kuti kunyange zvazvo aminoguanidine bicarbonate ichiratidza chivimbiso munzvimbo dzakasiyana-siyana, kumwe kutsvakurudza uye miedzo yekiriniki inodiwa kuti unzwisise zvizere kushanda kwayo uye kuchengeteka. Sezvinoita chero musanganiswa wemishonga, kunyatsoongorora uye kuongororwa kwakakosha kusati kwapararira kushandiswa kwezvinangwa zvekurapa.
Muchidimbu,aminoguanidine bicarbonate, ine CAS nhamba 2582-30-1, musanganiswa une mukana muminda yemishonga uye yekutsvagisa. Yayo anti-glycation, antioxidant uye anti-inflammatory properties inoita kuti ive mumiriri wekutsvaga mukugadzira mishonga yekurwisa zvirwere zvine chokuita nezera uye zvinetso zvechirwere cheshuga. Sezvo tsvakiridzo ichienderera mberi munzvimbo ino, aminoguanidine bicarbonate inogona kupa nzira nyowani dzekutonga kwehutano hwakasiyana, ichigadzira nzira yekufambira mberi kwekurapa.
Nguva yekutumira: May-30-2024