Chii chinonzi guanidineacetic acid?

Guanidineacetic acid (GAA),neChemical Abstracts Service (CAS) nhamba 352-97-6, ikomboni yakakwezva kutarisa munzvimbo dzakasiyana siyana, kunyanya biochemistry uye chikafu. Sechinobva kuguanidine, GAA inoita basa rakakosha mukuumbwa kwecreatine, komisheni yakakosha yemetabolism musimba retsandanyama. Kunzwisisa mabasa uye kushandiswa kwe guanidacetic acid kunogona kupa ruzivo mukukosha kwayo muhutano nekuvandudza kushanda.

Biochemistry

Guanidineacetic asidhiinonyanya kuzivikanwa nebasa rayo seyakatangira kusika. Creatine imorekuru rakakosha rinobatsira kugadzira adenosine triphosphate (ATP), iyo yekutanga simba inotakura mumaseru. Muviri unogadzira creatine kubva kuGAA muitsvo uye woiendesa kumamhasuru nehuropi. Iyi nzira yakakosha pakuchengetedza mazinga esimba uye kutsigira kugona kwekuziva panguva yekukwirira-kusimba maekisesaizi.

Kushandurwa kweGAA kuita creatine kunosanganisira akawanda enzymatic matanho, umo guanidinoacetate methyltransferase (GAMT) inoita basa rakakosha. Iyi enzyme inokonzeresa kutamiswa kweboka remethyl kubva kuS-adenosylmethionine kuenda kuguanidineacetic acid, ichigadzira creatine. Naizvozvo, GAA haingori musanganiswa wakapfava; iyo chikamu chakakosha chemaitiro emagetsi anochengetedza kugadzirwa kwesimba mumuviri.

Zvakanakira Movement uye Exercise

Nekuda kwebasa rayo mukugadzira synthesis, guanidine acetic acid inofarirwa nevamhanyi uye vanofarira kusimba. Kuwedzera neGAA kunogona kuwedzera kuita kwemuviri nekuwedzera kuwanikwa kwecreatine mumamhasuru. Izvi zvinovandudza simba, simba rekubuda, uye kutsungirira panguva yekushanda kwepamusoro-soro. Uyezve,GAAkuwedzeredza kunogona kubatsira kuderedza kuneta uye kukurumidza kupora mushure mekuita maekisesaizi, zvichiita kuti ive sarudzo inoyevedza kune avo vari kuita hurongwa hwekudzidzisa kwakasimba.

Tsvagiridzo inoratidza kuti GAA yekuwedzera inogona kuwedzera tsandanyama uye kugadzirisa kuumbwa kwemuviri. Izvi zvinonyanya kubatsira kune vatambi vanoda kuvandudza maitiro avo vachichengetedza muviri wakaonda. Pamusoro pezvo, GAA inotsigira basa rekuziva, iro rakakosha kune vatambi vanofanirwa kugara vakatarisa uye kufunga zvakajeka panguva yemakwikwi.

Inogona Kurapa Zvikumbiro

Pamusoro pemabhenefiti ayo ekuita maekisesaizi, zvinogona kurapa zvikumbiro zve guanidine acetic acid zviri kuongororwa zvakare. Zvimwe zvidzidzo zvinoratidza kuti GAA inogona kunge iine neuroprotective zvivakwa, zvichiita kuti ive mumiriri wekutsvaga muzvirwere zveurourodegenerative. Kugona kweGAA kuwedzera huropi hwekugadzira mazinga kunogona kupa dziviriro kubva kuzvirwere zvakaita seAlzheimer's neParkinson's disease, uko simba remetabolism rinowanzokanganiswa.

Uyezve, basa reGAAmukudzora kumwe kukanganiswa kwemetabolism kwakadzidzwawo. Kugona kwayo kupesvedzera simba remetabolism kunogona kuve nemhedzisiro yezvirwere zvakaita seshuga uko kushandiswa kwesimba kunokanganiswa. Nekuvandudza simba rekugadzira simba, GAA inogona kubatsira kubata zvirinani mazinga eshuga yeropa.

Mukupedzisa

Muchidimbu,guanidine acetate (GAA) musanganiswa une basa rakakosha rebiochemical, kunyanya seyakatangira kugadzira. Basa rayo musimba remetabolism rakakosha kune vatambi vari kutsvaga kuvandudza kuita uye kupora. Pamusoro pezvo, kuenderera mberi nekutsvagisa mukugona kwayo kwekurapa kunosimbisa kuchinjika kweGAA kupfuura chikafu chemitambo. Sezvo kunzwisisa kwedu kwekomisheni iyi kuri kuramba kuchishanduka, guanidine acetic acid inogona kuita basa rinowedzera kukosha mukuita kwemitambo uye manejimendi ehutano.

Contacting

Nguva yekutumira: Nov-04-2024