1. Whakamahia i roto i te rongoa rite te diuretic, pūnaha urinary anti-infective, whakamahia hoki rite te whakaahua tae whakawhanake stabilizer, whakamahia i roto i Paku mo whitening, freckle, tiaki makawe, etc.
2. He hydroquinone glycosylated i whakamahia ki te ako i te koiora melatonin me te aukati mo te tautuhi, te wehewehe me te tautuhi i te tyrosinase. Ko Arbutin he hydroquinone glycosylated i tangohia mai i te tipu bearberry. Ko te Arbutin he aukati tyrosinase e mohiotia ana, e aukati ana i te hanganga o te melanin. He maha nga wa e whakamahia ana a Arbutin hei kaihoko ma i roto i nga mahi whakapaipai.
3. Te aukati i te mahi melanocyte tyrosinase me te aukati i te hanga melanin ma te aukati i te synthase melanin.