Aminoguanidine bicarbonate,na usoro chemical CH6N4CO3 naNọmba CAS 2582-30-1, bụ ngwakọta nke mmasị maka ngwa ya dị iche iche na ọgwụ na nyocha. Ebumnuche nke isiokwu a bụ iwebata ngwaahịa aminoguanidine bicarbonate ma dokwuo anya ojiji na mkpa ha.
Aminoguanidine bicarbonatebụ ihe sitere na guanidine, ihe na-emekarị na osisi na microorganisms. Ọ bụ ntụ ntụ kristal na-acha ọcha nke na-adị ngwa ngwa na mmiri, na-eme ka ọ dị mfe iji mee ihe n'ụdị dị iche iche. Ngwakọta a adọtala mmasị maka ihe ndị nwere ike ime ọgwụ na ọrụ ya na nyocha na mmepe.
Otu n'ime isi ojiji nkeaminoguanidine bicarbonatedị na ngalaba ọgwụ. A mụọla ya maka ikike ya dị ka onye na-egbochi glycation, nke pụtara na ọ nwere ike inye aka gbochie ma ọ bụ belata mmepụta nke ngwaahịa njedebe glycation dị elu (AGE) n'ime ahụ. A na-ejikọta AGE na ọrịa dị iche iche metụtara afọ, dị ka ọrịa shuga, atherosclerosis, na ọrịa neurodegenerative. Site na igbochi nguzobe nke AGE, aminoguanidine bicarbonate na-egosi nkwa na-emepụta ọgwụ na-agwọ ọrịa ndị a.
Na mgbakwunye, a mụọla aminoguanidine bicarbonate cas 2582-30-1 maka ọrụ ọ nwere n'ịgwọ nsogbu ọrịa shuga. Ọrịa shuga nwere ike ibute nsogbu dị iche iche dịka ọrịa shuga nephropathy, retinopathy, na neuropathy, na aminoguanidine bicarbonate egosila ikike ibelata nsogbu ndị a site na antiglycation ya na ihe ndị na-akpata antioxidant. Nnyocha na mpaghara a na-egosi na ogige ahụ nwere ike ibelata nrụgide oxidative ma gbochie njikọ njikọ protein, isi ihe na-akpata nsogbu ọrịa shuga.
Na mgbakwunye na ngwa ọgwụ,aminoguanidine bicarbonatea na-eji na ntọala nyocha. A na-eji ya eme nchọpụta metụtara nrụgide oxidative, mbufụt na ọrịa ndị metụtara afọ. Ikike nke ogige ahụ iji gbanwee mmepụta nitric oxide na ihe ndị na-egbochi mkpali ya na-eme ka ọ bụrụ ngwá ọrụ bara uru maka ịghọta usoro ndị na-ebute ọrịa dị iche iche na ịmepụta ihe ndị nwere ike ịgwọ ọrịa.
Ọ dị mkpa iburu n'obi na ọ bụ ezie na aminoguanidine bicarbonate na-egosi nkwa n'akụkụ dị iche iche, a na-achọkwu nyocha na nyocha ụlọ ọgwụ iji ghọta nke ọma ịdị irè na nchekwa ya. Dịka ọ dị na ogige ọgwụ ọ bụla, nyocha nke ọma na nnwale dị oke mkpa tupu ejiri ya mee ihe maka ọgwụgwọ.
Na nchịkọta,aminoguanidine bicarbonate, nwere nọmba CAS 2582-30-1, bụ ngwakọta nwere ikike na mpaghara ọgwụ na nyocha. Ihe mgbochi glycation ya, antioxidant na mgbochi mkpali na-eme ka ọ bụrụ onye nyocha maka nyocha n'ime ọgwụ na-emepụta ọgwụ megide ọrịa ndị metụtara afọ na nsogbu nke ọrịa shuga. Ka nyocha na-aga n'ihu na mpaghara a, aminoguanidine bicarbonate nwere ike inye ụzọ ọhụrụ maka njikwa ọnọdụ ahụike dị iche iche, na-emeghe ụzọ maka ọganihu ọgwụgwọ ọgwụgwọ.
Oge nzipu: Mee-30-2024