5-Hydroxymethylfurfural (5-HMF), bụkwa CAS 67-47-0, bụ ihe sitere n'okike sitere na shuga. Ọ bụ isi etiti na mmepụta kemịkalụ dị iche iche, nke a na-eji dị ka ihe na-esi ísì ụtọ na ụlọ ọrụ nri, ma jiri ya mee ihe na nchịkọta ọgwụ dị iche iche na ụlọ ọrụ ọgwụ. Agbanyeghị, enwere nchegbu gbasara mmetụta 5-hydroxymethylfurfural nwere ike imebi ahụ ike mmadụ.
5-Hydroxymethylfurfurala na-ahụkarị n'ụdị nri dị iche iche a na-ekpo ọkụ, karịsịa ndị nwere shuga ma ọ bụ nnukwu fructose ọka sirop. Emebere ya n'oge mmeghachi omume Maillard, mmeghachi omume kemịkalụ n'etiti amino acid na mbelata shuga na-eme mgbe a na-ekpo ọkụ ma ọ bụ sie nri. N'ihi ya,5-HMFa na-ahụ ya n'ụdị nri ndị a na-edozi, gụnyere ihe ndị a na-eme achịcha, mkpụrụ osisi na akwụkwọ nri mkpọ, na kọfị.
Enwere ike imebi mmetụta nke5-hydroxymethylfurfuralabụrụla isiokwu nyocha na arụmụka sayensị. Ụfọdụ ọmụmụ na-atụ aro na ọkwa dị elu nke 5-HMF na nri nwere ike jikọta ya na mmetụta ahụike dị njọ, gụnyere genotoxicity na carcinogenicity. Genotoxicity na-ezo aka n'ikike kemịkalụ imebi ozi mkpụrụ ndụ ihe nketa n'ime mkpụrụ ndụ, nwere ike ibute mmụkọ ma ọ bụ kansa. Carcinogenicity, n'aka nke ọzọ, na-ezo aka n'ikike nke ihe na-akpata ọrịa cancer.
Otú ọ dị, ọ bụ ihe kwesịrị ịrịba ama na ọkwa nke5-hydroxymethylfurfuralN'ọtụtụ nri, a na-ewerekarị na ọ dị mma maka oriri mmadụ. Ụlọ ọrụ na-ahụ maka nchịkwa dị ka US Food and Drug Administration (FDA) na European Safety Authority (EFSA) ewepụtala ụkpụrụ nduzi maka ọkwa 5-HMF anabatara na nri. Ntuziaka ndị a dabere na nyocha sayensị sara mbara ma emebere ya iji hụ na nchekwa ndị ahịa.
Na mgbakwunye na ọnụnọ ya na nri, a na-eji 5-hydroxymethylfurfural eme ihe na ngwa ụlọ ọrụ dị iche iche. Ọ bụ isi etiti na-emepụta kemịkalụ furan, nke a na-eji eme resins, plastik na ọgwụ. A na-amụkwa 5-HMF dị ka kemịkalụ nke nwere bio dabere na mmepụta mmanụ ọkụ na kemịkalụ.
Ọ bụ ezie na e nwere nchegbu banyere emerụ mmetụta nke5-hydroxymethylfurfural, Ọ dị mkpa ịghọta na ogige a nwekwara ngwa ọrụ mmepụta ihe dị mkpa ma bụrụ ihe sitere n'okike nke nri na nri kpo oku. Dị ka ọ dị n'ọtụtụ kemịkalụ, isi ihe na-eme ka nchekwa dị mma bụ iji nlezianya nyochaa na ịhazi ọkwa ojiji ha na mkpughe.
Na nchịkọta, ebe enwere nchegbu ụfọdụ gbasara mmetụta ndị nwere ike imerụ ahụ5-hydroxymethylfurfural, karịsịa metụtara ọnụnọ ya na nri, ihe akaebe sayensị ugbu a na-egosi na ọ dị n'ọtụtụ ihe oriri na ọkwa a na-ewerekarị dị mma maka oriri mmadụ. Ụlọ ọrụ na-ahụ maka nchịkwa ewepụtala ụkpụrụ nduzi iji hụ na nchekwa ndị ahịa, na ọmụmụ ihe na-aga n'ihu iji ghọtakwuo mmetụta ahụike nke ogige ahụ. Dị ka ọ dị na kemịkal ọ bụla, ọ dị mkpa ịnọgide na-enyocha ojiji ya na ọkwa ikpughe iji hụ na nchekwa nke ndị na-azụ ahịa na ndị ọrụ na ụlọ ọrụ ahụ.
Oge nzipu: Mee-29-2024