Guanidinacetic acid (GAA),nrog Chemical Abstracts Service (CAS) tus lej 352-97-6, yog ib qho chaw uas tau nyiam nyob rau hauv ntau yam, tshwj xeeb tshaj yog biochemistry thiab khoom noj khoom haus. Raws li ib tug derivative ntawm guanidine, GAA plays ib tug tseem ceeb luag hauj lwm nyob rau hauv lub synthesis ntawm creatine, ib tug tseem ceeb compound rau lub zog metabolism hauv cov leeg nqaij. Kev nkag siab txog kev ua haujlwm thiab kev siv ntawm guanidacetic acid tuaj yeem muab kev pom rau nws qhov tseem ceeb hauv kev noj qab haus huv thiab txhim kho kev ua haujlwm.
Biochemistry
Guanidinacetic acidFeem ntau paub txog nws txoj haujlwm ua tus thawj coj rau creatine. Creatine yog ib qho tseem ceeb molecule uas pab tsim adenosine triphosphate (ATP), thawj lub zog thauj khoom hauv hlwb. Lub cev synthesizes creatine los ntawm GAA nyob rau hauv lub raum thiab thauj mus rau cov leeg thiab hlwb. Cov txheej txheem no tseem ceeb heev rau kev tswj hwm qib zog thiab txhawb kev paub txog kev ua haujlwm thaum lub zog siv zog.
Kev hloov pauv ntawm GAA rau creatine suav nrog ntau cov kauj ruam enzymatic, uas guanidinoacetate methyltransferase (GAMT) ua lub luag haujlwm tseem ceeb. Qhov no enzyme catalyzes kev hloov ntawm ib pawg methyl los ntawm S-adenosylmethionine rau guanidineacetic acid, tsim creatine. Yog li ntawd, GAA yog ntau tshaj li ib qho yooj yim compound; Nws yog ib qho tseem ceeb ntawm cov txheej txheem metabolic uas tswj lub zog tsim tawm hauv lub cev.
Cov txiaj ntsig ntawm kev txav thiab kev tawm dag zog
Vim nws lub luag haujlwm hauv creatine synthesis, guanidine acetic acid yog nrov nrog cov neeg ncaws pob thiab cov neeg nyiam kev tawm dag zog. Ntxiv nrog GAA tuaj yeem txhim kho lub cev kev ua haujlwm los ntawm kev ua kom muaj creatine hauv cov leeg. Qhov no txhim kho lub zog, lub zog tso zis, thiab kev ua siab ntev thaum lub sijhawm ua haujlwm siab. Ntxiv thiab,GAAKev ntxiv dag zog tuaj yeem pab txo qis qaug zog thiab rov ua kom rov qab sai tom qab kev tawm dag zog, ua rau nws yog qhov kev xaiv zoo rau cov neeg koom nrog kev kawm nruj.
Kev tshawb fawb qhia tau hais tias GAA supplementation tuaj yeem ua rau cov leeg nqaij thiab txhim kho lub cev muaj pes tsawg leeg. Qhov no tshwj xeeb tshaj yog muaj txiaj ntsig zoo rau cov neeg ncaws pob uas xav txhim kho lawv qhov kev ua tau zoo thaum tswj lub cev tsis muaj zog. Tsis tas li ntawd, GAA txhawb kev paub txog kev ua haujlwm, uas yog qhov tseem ceeb rau cov neeg ncaws pob uas yuav tsum tau nyob twj ywm thiab xav kom meej thaum sib tw.
Muaj peev xwm kho tau daim ntawv thov
Ntxiv rau nws cov txiaj ntsig kev tawm dag zog, kev siv tshuaj kho mob muaj peev xwm ntawm guanidine acetic acid kuj tau tshawb nrhiav. Qee cov kev tshawb fawb qhia tias GAA yuav muaj cov khoom tiv thaiv neuroprotective, ua rau nws yog tus neeg sib tw rau kev tshawb fawb txog cov kab mob neurodegenerative. GAA lub peev xwm los ua kom lub hlwb creatine ntau ntxiv tuaj yeem muab kev tiv thaiv kab mob xws li Alzheimer's thiab Parkinson's kab mob, qhov twg lub zog metabolism feem ntau cuam tshuam.
Tsis tas li ntawd, lub luag haujlwm ntawmGAAHauv kev tswj qee yam kab mob metabolic kuj tau kawm. Nws lub peev xwm los cuam tshuam cov metabolism hauv lub zog tuaj yeem cuam tshuam rau cov kab mob xws li ntshav qab zib uas siv lub zog cuam tshuam. Los ntawm kev txhim kho kev tsim hluav taws xob, GAA tuaj yeem pab tswj cov ntshav qab zib kom zoo dua.
Hauv kev xaus
Hauv cov ntsiab lus,Guanidine acetate (GAA) yog ib qho kev sib xyaw nrog cov haujlwm tseem ceeb ntawm biochemical, feem ntau ua tus ua ntej rau creatine. Nws lub luag haujlwm hauv lub zog metabolism yog qhov tseem ceeb rau cov neeg ncaws pob nrhiav kev txhim kho kev ua tau zoo thiab rov qab los. Tsis tas li ntawd, kev tshawb fawb txuas ntxiv mus rau nws qhov kev kho mob muaj peev xwm qhia txog qhov ua tau zoo ntawm GAA tshaj li kev noj zaub mov noj. Raws li peb txoj kev nkag siab ntawm qhov sib xyaw no txuas ntxiv mus, guanidine acetic acid tuaj yeem ua lub luag haujlwm tseem ceeb hauv kev ua kis las thiab kev tswj hwm kev noj qab haus huv.
Post lub sij hawm: Nov-04-2024