1. Hoʻohana ʻia i ka lāʻau lapaʻau e like me ka diuretic, urinary system anti-infective, hoʻohana ʻia hoʻi e like me ke kiʻi kala e hoʻomohala stabilizer, hoʻohana ʻia i nā mea hoʻonaninani no ka whitening, freckle, mālama lauoho, etc.
2. He hydroquinone glycosylated i hoʻohana ʻia no ke aʻo ʻana i ka biosynthesis melatonin a ma ke ʻano he mea paʻa no ka ʻike, ʻokoʻa a me ka ʻike ʻana i ka tyrosinase. ʻO Arbutin kahi hydroquinone glycosylated i unuhi ʻia mai ka mea kanu bearberry. ʻO Arbutin kahi mea paʻa tyrosinase i ʻike ʻia, ʻo ia ka mea e pale ai i ka hoʻokumu ʻana o ka melanin. Hoʻohana pinepine ʻia ʻo Arbutin ma ke ʻano he mea keʻokeʻo i nā mea hoʻonaninani.
3. Kāohi i ka hana melanocyte tyrosinase a pale i ka hana melanin ma ke kāohi ʻana i ka melanin synthase.