Zai iya amsawa tare da fluorine, maganin alkali mai ƙarfi da fuming sulfuric acid a 200 ℃.
Zai iya amsawa tare da yawancin marasa ƙarfe lokacin zafi.
Kauce wa lamba tare da oxides, halogens, alkalis, interhalogen mahadi, da nitrogen fluoride.
Tantalum yana da ƙarfi juriya ga ƙaƙƙarfan acid, musamman sulfuric acid.