Ana amfani da shi azaman ƙarfi, passivator na mai kara kuzari, ƙari na man fetur da mai mai, mai hana coking na tanderun fashewar ethylene da sashin tacewa, da sauransu.
An yi amfani da shi azaman wakili na wucewa don kaushi, masu kara kuzari, tsaka-tsakin magungunan kashe qwari, masu hana coking, da sauransu.
Dimethyl disulfide yana amsawa tare da cresol don samar da 2-methyl-4-hydroxybenzyl sulfide, wanda sannan ya haɗa tare da O, O-dimethylsulfurized phosphoryl chloride a cikin matsakaici na alkaline don samun thiophene.
Wannan ingantaccen magani ne kuma ƙarancin ƙwayar cuta na ƙwayoyin cuta na phosphorus tare da ingantaccen tasirin sarrafawa akan ƙwayar shinkafa, tsutsar waken soya, da tsutsa masu tashi. Hakanan za'a iya amfani dashi azaman maganin dabbobi don kawar da magudanar saniya da tsumman bangon saniya.